The effect of honey supplementation on drosophila melanogaster hemocyte count
Nirav Kottury, John Leddo
Immune diseases, particularly the COVID-19 pandemic, are a growing problem; according to the CDC, an estimated 3,049 people died daily from 2020 to 2021 of COVID-19 immune complications, surpassing death rates of even heart disease and cancer. As a result, many people have turned to honey to help boost immunity. Natural honey has remained a popular treatment for infected wounds and ingredient in numerous naturally-made immune medications, despite there being no justified studies on honey’s immune health benefits. Thus, there arises a need to confirm whether honey is safe to boost immunity. The effects of honey on Drosophila melanogaster’s immune system were tested. Hemocyte count was a proxy measurement for immune health; hemocytes are cells that destroy pathogens and trigger a fast-acting immune response. Using a needle to puncture the larvae, the hemocytes for each larva were drained into wells and evaluated by a cell counter. 80 trials were conducted for each of the two groups, and the 2061 hemocytes per larva for the non-honey-fed larvae was statistically significantly larger than the 1319 hemocytes per larva for the honey-fed larvae. Despite the long-held belief that honey is beneficial for the immune system, the research conducted supports the contrary.
Nirav Kottury, John Leddo. The effect of honey supplementation on drosophila melanogaster hemocyte count. International Journal of Advanced Educational Research, Volume 7, Issue 2, 2022, Pages 12-18